Yam contributes to improvement of glucose metabolism in rats
To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tend...
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my.iium.irep.248492013-01-17T08:04:47Z http://irep.iium.edu.my/24849/ Yam contributes to improvement of glucose metabolism in rats Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro QD Chemistry To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tended to be lower than that in the control diet. Insulin levels at 30 min and 60 min were significantly lower than those in the control group. In a long-term experiment, a normal diet (N) or 25% high fat diets with (Y) or without 15% yam powder (HF) were given to rats for 4 weeks. At 4 weeks, in an oral glucose tolerance test, the area under the curve (AUC) of plasma glucose level was higher in the HF group than that in the N group, whereas those in the Y groups did not differ from that in the N group. Glycosylated hemoglobin levels had similar tendency to the AUCs. Plasma leptin levels in the Y groups were significantly higher than that in the N group. In conclusion, yam may contribute to improvement of glucose metabolism. Additionally, we speculated that leptin level is possibly involved in the insulin-response to yam diets. Springer 2009 Article REM application/pdf en cc_by_nd http://irep.iium.edu.my/24849/1/fulltext.pdf Hashimoto, Naoto and Noda, Takahiro and Kim, Sun-Ju and Sarker, Md. Zaidul Islam and Yamauchi, Hiroaki and Takigawa, Shigenobu and Matsuura-Endo, Chie and Suzuki, Tatsuro and Han, Kyu-Ho and Fukushima, Michihiro (2009) Yam contributes to improvement of glucose metabolism in rats. Plant Foods for Human Nutrition, 64 (3). pp. 193-198. ISSN 0921-9668 http://dx.doi.org/10.1007/s11130-009-0126-z doi:10.1007/s11130-009-0126-z |
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QD Chemistry Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro Yam contributes to improvement of glucose metabolism in rats |
description |
To investigate whether yam improves glucose
metabolism, yam-containing diets were given to Wistar rats.
In a short-term experiment, fasted-rats were given 1.0 g of a
control and 20% yam-containing diets. At 60 min after start
of the feeding, glucose level in the yam diet group was
lower or tended to be lower than that in the control diet.
Insulin levels at 30 min and 60 min were significantly
lower than those in the control group. In a long-term
experiment, a normal diet (N) or 25% high fat diets with
(Y) or without 15% yam powder (HF) were given to rats for
4 weeks. At 4 weeks, in an oral glucose tolerance test, the
area under the curve (AUC) of plasma glucose level was
higher in the HF group than that in the N group, whereas
those in the Y groups did not differ from that in the N
group. Glycosylated hemoglobin levels had similar tendency
to the AUCs. Plasma leptin levels in the Y groups were
significantly higher than that in the N group. In conclusion,
yam may contribute to improvement of glucose metabolism.
Additionally, we speculated that leptin level is
possibly involved in the insulin-response to yam diets. |
format |
Article |
author |
Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro |
author_facet |
Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro |
author_sort |
Hashimoto, Naoto |
title |
Yam contributes to improvement of glucose metabolism in rats |
title_short |
Yam contributes to improvement of glucose metabolism in rats |
title_full |
Yam contributes to improvement of glucose metabolism in rats |
title_fullStr |
Yam contributes to improvement of glucose metabolism in rats |
title_full_unstemmed |
Yam contributes to improvement of glucose metabolism in rats |
title_sort |
yam contributes to improvement of glucose metabolism in rats |
publisher |
Springer |
publishDate |
2009 |
url |
http://irep.iium.edu.my/24849/1/fulltext.pdf http://irep.iium.edu.my/24849/ http://dx.doi.org/10.1007/s11130-009-0126-z |
_version_ |
1643608823828578304 |
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13.18916 |