Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations
Hepatocyte nuclear factor 1B (HNF1B) encodes a transcription factor expressed in developing human kidney epithelia. Heterozygous HNF1B mutations are the commonest monogenic cause of dysplastic kidney malformations (DKMs). To understand their pathobiology, we generated heterozygous HNF1B mutant kidne...
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| Language: | English English |
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Cell Press
2024
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| Online Access: | http://irep.iium.edu.my/112861/2/112861_Human%20pluripotent%20stem%20cell-derived%20kidney%20organoids.pdf http://irep.iium.edu.my/112861/3/112861_Human%20pluripotent%20stem%20cell-derived%20kidney%20organoids_Scopus.pdf http://irep.iium.edu.my/112861/ https://www.scopus.com/record/display.uri?eid=2-s2.0-85195081511&origin=resultslist&sort=plf-f&src=s&sid=9e43ac25bc62f5f1413107b4b4be2ef6&sot=b&sdt=b&s=TITLE-ABS-KEY%28Human+pluripotent+stem+cell-derived+kidney+organoids+reveal+tubular+epithelial+pathobiology+of+heterozygous+HNF1B-associated+dysplastic+kidney+malformations%29&sl=171&sessionSearchId=9e43ac25bc62f5f1413107b4b4be2ef6&relpos=0 |
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http://irep.iium.edu.my/112861/2/112861_Human%20pluripotent%20stem%20cell-derived%20kidney%20organoids.pdfhttp://irep.iium.edu.my/112861/3/112861_Human%20pluripotent%20stem%20cell-derived%20kidney%20organoids_Scopus.pdf
http://irep.iium.edu.my/112861/
https://www.scopus.com/record/display.uri?eid=2-s2.0-85195081511&origin=resultslist&sort=plf-f&src=s&sid=9e43ac25bc62f5f1413107b4b4be2ef6&sot=b&sdt=b&s=TITLE-ABS-KEY%28Human+pluripotent+stem+cell-derived+kidney+organoids+reveal+tubular+epithelial+pathobiology+of+heterozygous+HNF1B-associated+dysplastic+kidney+malformations%29&sl=171&sessionSearchId=9e43ac25bc62f5f1413107b4b4be2ef6&relpos=0