Application of chromatographic and spectroscopic-based methods for analysis of omega-3 (ω-3 FAs) and omega-6 (ω-6 FAs) fatty acids in marine natural products
Abstract: Omega-3 fatty acids v(ω-3 FAs) such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) and omega-6 fatty acids (ω-6 FAs) such as linoleic acid and arachidonic acid are important fatty acids responsible for positive effects on human health. The main sources of ω-3 FAs and ω-6 F...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI
2023
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Subjects: | |
Online Access: | http://irep.iium.edu.my/110863/2/110863_Application%20of%20chromatographic%20and%20spectroscopic-based.pdf http://irep.iium.edu.my/110863/ https://www.mdpi.com/1420-3049/28/14/5524 https://doi.org/10.3390/molecules28145524 |
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Summary: | Abstract: Omega-3 fatty acids v(ω-3 FAs) such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) and omega-6 fatty acids (ω-6 FAs) such as linoleic acid and arachidonic acid are
important fatty acids responsible for positive effects on human health. The main sources of ω-3
FAs and ω-6 FAs are marine-based products, especially fish oils. Some food, supplements, and
pharmaceutical products would include fish oils as a source of ω-3 FAs and ω-6 FAs; therefore, the
quality assurance of these products is highly required. Some analytical methods mainly based on
spectroscopic and chromatographic techniques have been reported. Molecular spectroscopy such as
Infrared and Raman parallel to chemometrics has been successfully applied for quantitative analysis
of individual and total ω-3 FAs and ω-6 FAs. This spectroscopic technique is typically applied as the
alternative method to official methods applying chromatographic methods. Due to the capability to
provide the separation of ω-3 FAs and ω-6 FAs from other components in the products, gas and liquid
chromatography along with sophisticated detectors such as mass spectrometers are ideal analytical
methods offering sensitive and specific results that are suitable for routine quality control. |
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