Retinoic acid targeting DGAT2 in non-alcoholic fatty liver disease model

• Main Authors: Ben Amer, Nawal Ahmed Mohamed, Buyong, Zunariah, Abdullah, Nor Zamzila, Hamdan, Asmah Hanim, Ab Rahman, Jamalludin, Kuttulebbai Naina Mohamed Salam, Sirajudeen
• Format: Article
• Language: English
• Published: Faculty of Medicine, UKM 2023
• Subjects: R Medicine (General); RB Pathology; RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/110140/1/110140_Retinoic%20acid%20targeting%20DGAT2.pdf; http://irep.iium.edu.my/110140/; https://www.medicineandhealthukm.com/article/international-virtual-medical-research-symposium

Introduction: Nonalcoholic fatty liver disease (NAFLD) is caused by triglyceride (TG) accumulation in the hepatocyte. The initial reversible stage is steatosis, and if left untreated may progress to steatohepatitis, marked by necrosis and inflammation, eventually leading to cirrhosis. Currently, the...