Compounding and characterization of oral disintegrating films containing memantine hydrochloride for geriatrics

• Main Authors: Mohd Rofiq, Hanifah, Phang, Hiu Ching, Janakiraman, Ashok Kumar, Chew, Yik-Ling, Helal Uddin, A.B.M., Sarker, Md. Zaidul Islam, Lee, Siew-Keah, Liew, Kai Bin
• Format: Article
• Language: English
• Published: International Journal of Pharmaceutical Compounding 2023
• Subjects: QD Chemistry; RS Pharmacy and materia medica; RS192 Materia Medica-Pharmaceutical Technology; RS403 Materia Medica-Pharmaceutical Chemistry
• Online Access: http://irep.iium.edu.my/108958/13/108958_Compounding%20and%20characterization%20of%20oral%20disintegrating%20films.pdf; http://irep.iium.edu.my/108958/; https://ijpc.com/Abstracts/Abstract.cfm?ABS=5280

Memantine hydrochloride is commonly prescribed for Alzheimer’s disease and vascular dementia. However, the drug is only available in tablet form, a dosage form which is difficult for geriatrics to swallow. This problem is especially difficult for those patients diagnosed with Alzheimer’s. This study...