Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT)

Background: Methadone is a substrate of the permeability glycoprotein (P-gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. Large interindividual variability in serum methadone levels for therapeutic response has been reported. Genetic variations in ABCB1 gene may be responsible for...

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Main Authors: Nasir, Mohamad, Zalina, Zahari, Lee, Chee Siong
Format: Article
Language:English
English
English
Published: Taylor and Francis Ltd 2016
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Online Access:http://eprints.unisza.edu.my/7471/1/FH02-FP-16-06142.jpg
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http://eprints.unisza.edu.my/7471/
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