Isolation and cytotoxic investigation of new carbazole alkaloids from Murraya koenigii (Linn.) Spreng
Six new carbazole alkaloids, murrastanine-A (1), murrastinine-A, -B, -C (2–4), murrayatanine-A (5) and bismahanimboline (6), were isolated from the bark and leaves of Murraya koenigii (Linn.) Spreng along with 24 known carbazole alkaloids. The structure of these compounds were elucidated by extensiv...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Elsevier Science
2015
|
| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/6030/1/FH02-FBIM-15-03474.jpg http://eprints.unisza.edu.my/6030/2/FH02-FBIM-15-04198.jpg http://eprints.unisza.edu.my/6030/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Six new carbazole alkaloids, murrastanine-A (1), murrastinine-A, -B, -C (2–4), murrayatanine-A (5) and bismahanimboline (6), were isolated from the bark and leaves of Murraya koenigii (Linn.) Spreng along with 24 known carbazole alkaloids. The structure of these compounds were elucidated by extensive spectroscopic analysis. Murrastinine-C (4) and murrayatanine-A (5) exhibited cytotoxic activity against HL-60 and HeLa (CD50<20 μg/mL) via MTT assay. |
|---|