Squamous cell carcinoma of the tongue in a patient with rothmund-thomson syndrome (Recq4 Mutation) - intolerance to radiotherapy

We report a case of squamous cell carcinoma of the base of the tongue in a 27 years old patient with Rothmund-Thomson syndrome (RTS). An abnormal DNA repair mechanism in some RTS patients predispose them to malignancy and influence the tolerance to radiotherapy.

Saved in:
Bibliographic Details
Main Authors: Hamidah A,, Mazlina M,, Zarina AL,, Muhaizan WM,, Fuad I,, Jamal R,
Format: Article
Language:English
Published: Penerbit UKM 2009
Online Access:http://journalarticle.ukm.my/1952/1/04-4%282%29_~_MS_085_%2864-75%29.pdf
http://journalarticle.ukm.my/1952/
http://www.ppukm.ukm.my/ukmmcjournal/index.php
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report a case of squamous cell carcinoma of the base of the tongue in a 27 years old patient with Rothmund-Thomson syndrome (RTS). An abnormal DNA repair mechanism in some RTS patients predispose them to malignancy and influence the tolerance to radiotherapy.