Squamous cell carcinoma of the tongue in a patient with rothmund-thomson syndrome (Recq4 Mutation) - intolerance to radiotherapy
We report a case of squamous cell carcinoma of the base of the tongue in a 27 years old patient with Rothmund-Thomson syndrome (RTS). An abnormal DNA repair mechanism in some RTS patients predispose them to malignancy and influence the tolerance to radiotherapy.
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit UKM
2009
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| Online Access: | http://journalarticle.ukm.my/1952/1/04-4%282%29_~_MS_085_%2864-75%29.pdf http://journalarticle.ukm.my/1952/ http://www.ppukm.ukm.my/ukmmcjournal/index.php |
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| Summary: | We report a case of squamous cell carcinoma of the base of the tongue in a 27 years old patient with Rothmund-Thomson syndrome (RTS). An abnormal DNA repair mechanism in some RTS patients predispose them to malignancy and influence the tolerance to radiotherapy. |
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