Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study

• Main Authors: Mohamad Ariff Mohamad Yussoff,, Azzmer Azzar Abd Hamid,, Shafida Abd Hamid,, Khairul Bariyyah Abd Halim,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2020
• Online Access: http://journalarticle.ukm.my/15184/1/ARTIKEL%208.pdf; http://journalarticle.ukm.my/15184/; http://www.ukm.my/jsm/malay_journals/jilid49bil3_2020/KandunganJilid49Bil3_2020.html

Interaction of Ebola virus matrix protein VP40 with RNA is crucial in the early infection stage to facilitate the transcription of the viral gene. Thus, VP40 is a promising target to inhibit the Ebola virus from spreading. This study aims to identify and optimize ligands that can potentially block t...