Identification of missense mutations in genes related to cancer pathways in glioma

• Main Authors: Nor Azian Abdul Murad,, Saiful Effendi Syafruddin,, Muhiddin Ishak,, Mohd Ridhwan Abdul Razak,, Sri Noraima Othman,, Soon, Bee Hong, Azizi Abu Bakar,, Farizal Fadzil,, Jegan Thanabalan,, Toh, Charng Jeng, Isa Mohamed Rose,, Roslan Harun,, Rahman Jamal,
• Format: Article
• Language: English
• Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2016
• Online Access: http://journalarticle.ukm.my/13240/1/25-54-1-SM.pdf; http://journalarticle.ukm.my/13240/; http://spaj.ukm.my/apjmm/index.php/apjmm/issue/view/10

Glioma is the most common primary brain tumour of the central nervous system. Many genetic alterations and mutations have been identified in glioma using various approaches. We performed DNA sequencing on the tumours of 16 patients with Grade I, II, III and IV glioma. The AmpliSeq Cancer Primers Poo...