Nanoparticle-laden contact lens for controlled release of vancomycin with enhanced antibiotic efficacy

• Main Authors: Tong, W.Y., Tan, W.-N., Kamarul Azizi, M.A., Leong, C.R., El Azab, I.H., Lim, J.W., Mahmoud, M.H.H., Dailin, D.J., Ibrahim, M.M., Chuah, L.F.
• Format: Article
• Published: Elsevier Ltd 2023
• Online Access: http://scholars.utp.edu.my/id/eprint/37337/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164711712&doi=10.1016%2fj.chemosphere.2023.139492&partnerID=40&md5=d7013147b9cf695969c34182eda4fe6b

Vancomycin is the last resort antibiotic for the treatment of severe bacterial keratitis. Its clinical application is limited due to its hydrophilicity and high molecular weight. To overcome this, this study aims to develop nanoparticles-laden contact lens for controlled ocular delivery of vancomyci...