Preparation of Chitosan-Tripolyphosphate Formulated Insulin Microparticles, Their Characterization, ANN Prediction, and Release Kinetics

Purpose: Insulin is highly sensitive to an acidic pH medium and degrades faster. The encapsulation of insulin with chitosan (CS) particulates could partially solve this issue. Since the formation of particles involves different parameters, the unoptimized parameters and formulation result in unstabl...

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Bibliographic Details
Main Authors: Safdar, R., Thanabalan, M.
Format: Article
Published: 2023
Online Access:http://scholars.utp.edu.my/id/eprint/34350/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146554664&doi=10.1007%2fs12247-023-09707-8&partnerID=40&md5=6ef043acd4dade401ec5e2ef20e1a721
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