Transformation of Hydrophilic Drug into Oil-Miscible Ionic Liquids for Transdermal Drug Delivery

• Main Authors: Md Moshikur, R., Shimul, I.M., Uddin, S., Wakabayashi, R., Moniruzzaman, M., Goto, M.
• Format: Article
• Published: 2022
• Online Access: http://scholars.utp.edu.my/id/eprint/34266/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144506615&doi=10.1021%2facsami.2c15636&partnerID=40&md5=57d340b7a7c3873d70a546a596a84c5b

The transdermal delivery of hydrophilic drugs remains challenging owing to their poor ability to permeate the skin; formulation with oil media is difficult without adding chemical permeation enhancers or co-solvents. Herein, we synthesized 12 oil-miscible ionic liquid (IL) drugs comprising lidocaine...