Predicting the solubility of pharmaceutical compound in ionic liquids using COSMo-RS model

• Main Authors: Lotfi, M., Moniruzzaman, M., Abdul Mutalib, M.I.B., Rajabi, M.S.
• Format: Article
• Published: Asian Research Publishing Network 2016
• Online Access: http://scholars.utp.edu.my/id/eprint/25545/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959450222&partnerID=40&md5=1222631f4846c2eb93d9182dc63c1cdb

One conventional way to address the poor solubility of drugs in order to increase their performance is to use excipients polar organic solvents. However, the use of such organic solvents has many drawbacks. They are often volatile, flammable and toxic. Pharmaceutical ingredients must be free from al...