Formulation and characterization of acetate based ionic liquid in oil microemulsion as a carrier for acyclovir and methotrexate

• Main Authors: Kandasamy, S., Moniruzzaman, M., Sivapragasam, M., Shamsuddin, M.R., Mutalib, M.I.A.
• Format: Article
• Published: Elsevier B.V. 2018
• Online Access: http://scholars.utp.edu.my/id/eprint/21574/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028302500&doi=10.1016%2fj.seppur.2017.08.044&partnerID=40&md5=2a8a7d0627e5e9fbf4794a9036b0a71d

Ionic Liquid (ILs) in oil microemulsions (IL/O MEs) have emerged as a potential carrier for transdermal drug delivery, particularly for sparingly soluble drug molecules, such as acyclovir and methotrexate. However, less attention was paid in the selection of non-toxic and biodegradable ILs. In this...