Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked...
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Nature Publishing Group
2015
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my.utp.eprints.314082022-03-26T03:19:00Z Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation Savall, J. Ho, E.T.W. Huang, C. Maxey, J.R. Schnitzer, M.J. We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns. © 2015 Nature America, Inc. All rights reserved. Nature Publishing Group 2015 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90 Savall, J. and Ho, E.T.W. and Huang, C. and Maxey, J.R. and Schnitzer, M.J. (2015) Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation. Nature Methods, 12 (7). pp. 657-660. http://eprints.utp.edu.my/31408/ |
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We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns. © 2015 Nature America, Inc. All rights reserved. |
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Article |
author |
Savall, J. Ho, E.T.W. Huang, C. Maxey, J.R. Schnitzer, M.J. |
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Savall, J. Ho, E.T.W. Huang, C. Maxey, J.R. Schnitzer, M.J. Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
author_facet |
Savall, J. Ho, E.T.W. Huang, C. Maxey, J.R. Schnitzer, M.J. |
author_sort |
Savall, J. |
title |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
title_short |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
title_full |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
title_fullStr |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
title_full_unstemmed |
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation |
title_sort |
dexterous robotic manipulation of alert adult drosophila for high-content experimentation |
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Nature Publishing Group |
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2015 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90 http://eprints.utp.edu.my/31408/ |
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