Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods
This study aims to evaluate the emollient properties of natural-based oil creams on skin conditions. The focus is primarily on natural virgin coconut oil (VCO) and structured VCO (SVCO) which contain medium-chain triglycerides (MCTs) that have been reported to have a permeation enhancement effect on...
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Malaysian Society of Applied Biology
2022
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Online Access: | http://eprints.utm.my/id/eprint/98802/1/JuanMatmin2022_EnhancingEmollientPropertiesofNatural.pdf http://eprints.utm.my/id/eprint/98802/ http://dx.doi.org/10.55230/mabjournal.v51i4.18 |
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my.utm.988022023-02-02T09:03:14Z http://eprints.utm.my/id/eprint/98802/ Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods Ibrahim, Salizatul Ilyana Matmin, Juan Hairul, Nuriana Munirah Abdul Majeed, Abu Bakar QD Chemistry This study aims to evaluate the emollient properties of natural-based oil creams on skin conditions. The focus is primarily on natural virgin coconut oil (VCO) and structured VCO (SVCO) which contain medium-chain triglycerides (MCTs) that have been reported to have a permeation enhancement effect on the lipophilic active ingredient. SVCO, which contains a higher amount of MCTs than VCO, was produced by lipase-catalyzed acidolysis of caprylic/octanoic acid (eight-carbon chain) and VCO. The emollient cream was prepared using the oil in water (o/w) formulation cream and it consisted of 30% (w/w) of oils, emulsifying wax, and deionized water. While in the oil phase, 5% (w/w) α-tocopherol, the model lipophilic active ingredient was added to the cream. Significant effects (p<0.05) were statistically produced in the skin moisture content, transepidermal water loss (TEWL), and skin elasticity values for all formulations as compared to the skin at T0 (before application) after the short-and long-term study periods. The skin smoothness (SEsm) and skin roughness (SEr) values, which are indicators of the skin condition, also showed significant improvement. The results indicated that VCO and SVCO creams exerted an emollient effect when applied topically and also acted as skin permeation enhancers in the formulation. Malaysian Society of Applied Biology 2022 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/98802/1/JuanMatmin2022_EnhancingEmollientPropertiesofNatural.pdf Ibrahim, Salizatul Ilyana and Matmin, Juan and Hairul, Nuriana Munirah and Abdul Majeed, Abu Bakar (2022) Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods. Malaysian Applied Biology, 51 (4). pp. 109-117. ISSN 0126-8643 http://dx.doi.org/10.55230/mabjournal.v51i4.18 DOI: 10.55230/mabjournal.v51i4.18 |
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QD Chemistry Ibrahim, Salizatul Ilyana Matmin, Juan Hairul, Nuriana Munirah Abdul Majeed, Abu Bakar Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
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This study aims to evaluate the emollient properties of natural-based oil creams on skin conditions. The focus is primarily on natural virgin coconut oil (VCO) and structured VCO (SVCO) which contain medium-chain triglycerides (MCTs) that have been reported to have a permeation enhancement effect on the lipophilic active ingredient. SVCO, which contains a higher amount of MCTs than VCO, was produced by lipase-catalyzed acidolysis of caprylic/octanoic acid (eight-carbon chain) and VCO. The emollient cream was prepared using the oil in water (o/w) formulation cream and it consisted of 30% (w/w) of oils, emulsifying wax, and deionized water. While in the oil phase, 5% (w/w) α-tocopherol, the model lipophilic active ingredient was added to the cream. Significant effects (p<0.05) were statistically produced in the skin moisture content, transepidermal water loss (TEWL), and skin elasticity values for all formulations as compared to the skin at T0 (before application) after the short-and long-term study periods. The skin smoothness (SEsm) and skin roughness (SEr) values, which are indicators of the skin condition, also showed significant improvement. The results indicated that VCO and SVCO creams exerted an emollient effect when applied topically and also acted as skin permeation enhancers in the formulation. |
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Article |
author |
Ibrahim, Salizatul Ilyana Matmin, Juan Hairul, Nuriana Munirah Abdul Majeed, Abu Bakar |
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Ibrahim, Salizatul Ilyana Matmin, Juan Hairul, Nuriana Munirah Abdul Majeed, Abu Bakar |
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Ibrahim, Salizatul Ilyana |
title |
Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
title_short |
Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
title_full |
Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
title_fullStr |
Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
title_full_unstemmed |
Enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
title_sort |
enhancing emollient properties of natural and structured virgin coconut oil creams on skin conditions using non-invasive skin biophysical methods |
publisher |
Malaysian Society of Applied Biology |
publishDate |
2022 |
url |
http://eprints.utm.my/id/eprint/98802/1/JuanMatmin2022_EnhancingEmollientPropertiesofNatural.pdf http://eprints.utm.my/id/eprint/98802/ http://dx.doi.org/10.55230/mabjournal.v51i4.18 |
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