Electrospun nanofiber and cryogel of polyvinyl alcohol transdermal patch containing diclofenac sodium: Preparation, characterization and in vitro release studies

• Main Authors: Sa’adon, Shafizah, Mohamed Ansari, Mohamed Nainar, Abd. Razak, Saiful Izwan, Mohd. Yusof, Abdul Halim, Mohd. Faudzi, Ahmad Athif, Sagadevan, Suresh, Mat Nayan, Nadirul Hasraf, Anand, Joseph Sahaya, Mat Amin, Khairul Anuar
• Format: Article
• Language: English
• Published: MDPI 2021
• Subjects: QM Human anatomy
• Online Access: http://eprints.utm.my/id/eprint/97571/1/SaifulIzwan2021_ElectrospunNanofiberandCryogelofPolyvinylAlcohol.pdf; http://eprints.utm.my/id/eprint/97571/; http://dx.doi.org/10.3390/pharmaceutics13111900

Transdermal drug delivery systems (TDDS) have drawn more interest from pharmaceutical scientists because they could provide steady blood levels and prevent the first-pass metabolism over a longer period. Polyvinyl alcohol (PVA) has been widely used in this application due to its biocompatibility, no...