Cover Image

Two-dimensional signal transduction during the formation of invadopodia

Signal transduction is an important process associated with invadopodia formation which consequently leads to cancer cell invasion. In this study, a two-dimensional free boundary problem in a steady-case of signal trans- duction during the formation of invadopodia is investigated. The signal equatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Noor Azhuan, N. A., Poignard, C., Suzuki, T., Shafie, S., Admon, M. A.
Format: Article
Published: Universiti Putra Malaysia 2019
Subjects:
QA Mathematics
Online Access:http://eprints.utm.my/id/eprint/96982/
https://einspem.upm.edu.my/journal/volume13.2may.php
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.utm.96982
record_format eprints
spelling my.utm.969822022-09-06T07:53:42Z http://eprints.utm.my/id/eprint/96982/ Two-dimensional signal transduction during the formation of invadopodia Noor Azhuan, N. A. Poignard, C. Suzuki, T. Shafie, S. Admon, M. A. QA Mathematics Signal transduction is an important process associated with invadopodia formation which consequently leads to cancer cell invasion. In this study, a two-dimensional free boundary problem in a steady-case of signal trans- duction during the formation of invadopodia is investigated. The signal equation is represented by a Laplace equation with Dirichlet boundary condition. The plasma membrane is taken as zero level set function. The level set method is used to solve the complete model numerically. Our results showed that protrusions are developed on the membrane surface due to the presence of signal density inside the cell. Universiti Putra Malaysia 2019 Article PeerReviewed Noor Azhuan, N. A. and Poignard, C. and Suzuki, T. and Shafie, S. and Admon, M. A. (2019) Two-dimensional signal transduction during the formation of invadopodia. Malaysian Journal of Mathematical Sciences, 13 (2). pp. 155-164. ISSN 1823-8343 https://einspem.upm.edu.my/journal/volume13.2may.php NA
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QA Mathematics
spellingShingle QA Mathematics
Noor Azhuan, N. A.
Poignard, C.
Suzuki, T.
Shafie, S.
Admon, M. A.
Two-dimensional signal transduction during the formation of invadopodia
description Signal transduction is an important process associated with invadopodia formation which consequently leads to cancer cell invasion. In this study, a two-dimensional free boundary problem in a steady-case of signal trans- duction during the formation of invadopodia is investigated. The signal equation is represented by a Laplace equation with Dirichlet boundary condition. The plasma membrane is taken as zero level set function. The level set method is used to solve the complete model numerically. Our results showed that protrusions are developed on the membrane surface due to the presence of signal density inside the cell.
format Article
author Noor Azhuan, N. A.
Poignard, C.
Suzuki, T.
Shafie, S.
Admon, M. A.
author_facet Noor Azhuan, N. A.
Poignard, C.
Suzuki, T.
Shafie, S.
Admon, M. A.
author_sort Noor Azhuan, N. A.
title Two-dimensional signal transduction during the formation of invadopodia
title_short Two-dimensional signal transduction during the formation of invadopodia
title_full Two-dimensional signal transduction during the formation of invadopodia
title_fullStr Two-dimensional signal transduction during the formation of invadopodia
title_full_unstemmed Two-dimensional signal transduction during the formation of invadopodia
title_sort two-dimensional signal transduction during the formation of invadopodia
publisher Universiti Putra Malaysia
publishDate 2019
url http://eprints.utm.my/id/eprint/96982/
https://einspem.upm.edu.my/journal/volume13.2may.php
_version_ 1744353697882701824
score 13.214268

Similar Items