Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis
One of the major drawbacks of electrophoresis in both capillary and microchip is the unsatisfactory sensitivity. Online sample preconcentration techniques can be regarded as the most common and powerful approaches commonly applied to enhance overall detection sensitivity. While the advances of vario...
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my.utm.960112022-07-01T08:22:06Z http://eprints.utm.my/id/eprint/96011/ Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis John, Annestasia Simbut Sidek, Mohammad Mizwaruddin Thang, Lee Yien Sami, Sabita Tey, Hui Yin See, Hong Heng QD Chemistry One of the major drawbacks of electrophoresis in both capillary and microchip is the unsatisfactory sensitivity. Online sample preconcentration techniques can be regarded as the most common and powerful approaches commonly applied to enhance overall detection sensitivity. While the advances of various online preconcentration strategies in capillary and microchip employing aqueous background electrolytes are well-reviewed, there has been limited discussion of the feasible preconcentration techniques specifically developed for capillary and microchip using nonaqueous background electrolytes. This review provides the first consolidated overview of various online preconcentration techniques in nonaqueous capillary and microchip electrophoresis, covering the period of the last two decades. It covers developments in the field of sample stacking, isotachophoresis, and micellar-based stacking. Attention is also given to multi-stacking strategies that have been used for nonaqueous electrophoresis. Elsevier B.V. 2021 Article PeerReviewed John, Annestasia Simbut and Sidek, Mohammad Mizwaruddin and Thang, Lee Yien and Sami, Sabita and Tey, Hui Yin and See, Hong Heng (2021) Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis. Journal of Chromatography A, 1638 . p. 461868. ISSN 0021-9673 http://dx.doi.org/10.1016/j.chroma.2020.461868 |
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One of the major drawbacks of electrophoresis in both capillary and microchip is the unsatisfactory sensitivity. Online sample preconcentration techniques can be regarded as the most common and powerful approaches commonly applied to enhance overall detection sensitivity. While the advances of various online preconcentration strategies in capillary and microchip employing aqueous background electrolytes are well-reviewed, there has been limited discussion of the feasible preconcentration techniques specifically developed for capillary and microchip using nonaqueous background electrolytes. This review provides the first consolidated overview of various online preconcentration techniques in nonaqueous capillary and microchip electrophoresis, covering the period of the last two decades. It covers developments in the field of sample stacking, isotachophoresis, and micellar-based stacking. Attention is also given to multi-stacking strategies that have been used for nonaqueous electrophoresis. |
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Article |
author |
John, Annestasia Simbut Sidek, Mohammad Mizwaruddin Thang, Lee Yien Sami, Sabita Tey, Hui Yin See, Hong Heng |
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John, Annestasia Simbut Sidek, Mohammad Mizwaruddin Thang, Lee Yien Sami, Sabita Tey, Hui Yin See, Hong Heng |
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John, Annestasia Simbut |
title |
Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
title_short |
Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
title_full |
Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
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Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
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Online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
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online sample preconcentration techniques in nonaqueous capillary and microchip electrophoresis |
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Elsevier B.V. |
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2021 |
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http://eprints.utm.my/id/eprint/96011/ http://dx.doi.org/10.1016/j.chroma.2020.461868 |
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