Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation
Introduction Nigella sativa (NS) is widely known to have anti-inflammatory effects on various inflammation models; however, there are no known NS studies that include EIMD as a model of inflammation. This study aimed to investigate the effects of NS on EIMD as a model of inflammation. Material and M...
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my.utm.936882021-12-31T08:45:21Z http://eprints.utm.my/id/eprint/93688/ Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation Raimi, Fatihah Jawis, Mohd. Nidzam Hashim, Hairulanuar Zainuddin, Zainalabidin LB Theory and practice of education Introduction Nigella sativa (NS) is widely known to have anti-inflammatory effects on various inflammation models; however, there are no known NS studies that include EIMD as a model of inflammation. This study aimed to investigate the effects of NS on EIMD as a model of inflammation. Material and Methods A total of 33 youth football athletes were assigned to three groups (i.e., NS3000, NS1500, and the control). All groups performed 10 sets of 10 repetitions of CMJ (with a 30-s intermittent rest between sets) by adopting a squat stance in starting and landing positions to induce muscle damage. Immediately after the exercise, they were administered a single dose of either 3000 mg or 1500 mg of NS or a placebo. A set of tests was conducted to measure muscular power, soreness, tenderness, thigh circumference, ROM, serum CK, and LDH at pre-exercise, 30 min, 1 d, 2 d, 3 d, and 4 d post-exercise. Results Changes in these variables over time were compared by a mixed factorial ANOVA. As expected, exercise decreased muscular power and ROM (30 min to 1 d post-exercise) (P < 0.05) and increased soreness, tenderness, thigh circumference, CK, and LDH (30 min to 1 d post-exercise) (P [removed] 0.05). Discussions and Conclusion The obtained results suggested that the CMJ protocol used in this study was sufficient to induce muscle damage. Thus,EIMD can be used as a model of inflammation; however, a single one-off intake of NS does not attenuate the indirect markers of EIMD. The effective dosage of NS to increase the recovery speed was not determined. Editura Universitatii din Pitesti 2020 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/93688/1/ZainalAbidin2020_SingleOneOffDoseOfNigellaSativa.pdf Raimi, Fatihah and Jawis, Mohd. Nidzam and Hashim, Hairulanuar and Zainuddin, Zainalabidin (2020) Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation. Journal of Physical Education and Sport, 20 (3). pp. 1444-1454. ISSN 2247-8051 http://dx.doi.org/10.7752/jpes.2020.03199 |
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LB Theory and practice of education Raimi, Fatihah Jawis, Mohd. Nidzam Hashim, Hairulanuar Zainuddin, Zainalabidin Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
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Introduction Nigella sativa (NS) is widely known to have anti-inflammatory effects on various inflammation models; however, there are no known NS studies that include EIMD as a model of inflammation. This study aimed to investigate the effects of NS on EIMD as a model of inflammation. Material and Methods A total of 33 youth football athletes were assigned to three groups (i.e., NS3000, NS1500, and the control). All groups performed 10 sets of 10 repetitions of CMJ (with a 30-s intermittent rest between sets) by adopting a squat stance in starting and landing positions to induce muscle damage. Immediately after the exercise, they were administered a single dose of either 3000 mg or 1500 mg of NS or a placebo. A set of tests was conducted to measure muscular power, soreness, tenderness, thigh circumference, ROM, serum CK, and LDH at pre-exercise, 30 min, 1 d, 2 d, 3 d, and 4 d post-exercise. Results Changes in these variables over time were compared by a mixed factorial ANOVA. As expected, exercise decreased muscular power and ROM (30 min to 1 d post-exercise) (P < 0.05) and increased soreness, tenderness, thigh circumference, CK, and LDH (30 min to 1 d post-exercise) (P [removed] 0.05). Discussions and Conclusion The obtained results suggested that the CMJ protocol used in this study was sufficient to induce muscle damage. Thus,EIMD can be used as a model of inflammation; however, a single one-off intake of NS does not attenuate the indirect markers of EIMD. The effective dosage of NS to increase the recovery speed was not determined. |
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Article |
author |
Raimi, Fatihah Jawis, Mohd. Nidzam Hashim, Hairulanuar Zainuddin, Zainalabidin |
author_facet |
Raimi, Fatihah Jawis, Mohd. Nidzam Hashim, Hairulanuar Zainuddin, Zainalabidin |
author_sort |
Raimi, Fatihah |
title |
Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
title_short |
Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
title_full |
Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
title_fullStr |
Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
title_full_unstemmed |
Single one-off dose of Nigella Sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
title_sort |
single one-off dose of nigella sativa does not attenuate indirect markers of exercise-induced muscle damage as a model of inflammation |
publisher |
Editura Universitatii din Pitesti |
publishDate |
2020 |
url |
http://eprints.utm.my/id/eprint/93688/1/ZainalAbidin2020_SingleOneOffDoseOfNigellaSativa.pdf http://eprints.utm.my/id/eprint/93688/ http://dx.doi.org/10.7752/jpes.2020.03199 |
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13.160551 |