Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia

The root of Eurycoma longifolia or locally called as Tongkat Ali contains numerous health benefits, mainly due to the bioactive compounds. The main compound of interest is from the group of quassinoids which is also known as degraded triterpenoids such as eurycomanone, eurycomalactone, longilactone,...

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Main Authors: Mohd. Ismail, Nurul Izzati, Lee, Suan Chua
Format: Conference or Workshop Item
Language:English
Published: 2020
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Online Access:http://eprints.utm.my/id/eprint/92889/1/ChuaLeeSuan2020_SolventPartitionforTerpenoidRichFraction.pdf
http://eprints.utm.my/id/eprint/92889/
http://dx.doi.org/10.2991/aer.k.201229.009
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spelling my.utm.928892021-10-28T10:18:15Z http://eprints.utm.my/id/eprint/92889/ Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia Mohd. Ismail, Nurul Izzati Lee, Suan Chua TP Chemical technology The root of Eurycoma longifolia or locally called as Tongkat Ali contains numerous health benefits, mainly due to the bioactive compounds. The main compound of interest is from the group of quassinoids which is also known as degraded triterpenoids such as eurycomanone, eurycomalactone, longilactone, pasakbumin B and pasakbumin C. Quassinoids or degraded triterpenoids were reported to possess anti-malarial, anti-diabetic, anti-bacterial and anti-cancer effects. Therefore, it is important to concentrate terpenoids rich fraction from the crude extract of E. longifolia roots to enhance the reported bioactivities. The present study was carried out to determine the suitable solvent in concentrating terpenoids from the crude extract of E. longifolia roots. Organic solvents such as chloroform, butanol and ethyl acetate were selected to maximally recover terpenoids based on the principle of liquid-liquid extraction. The quality of the fractions was compared and analysed for the phytochemical composition. The results showed all organic fractions contained higher total terpenoid content than its aqueous counterpart. The chloroform fraction exhibited the highest yield of mass fraction (72.90 ± 0.15%) and the highest total terpenoid content (0.47 ± 0.01 mg OAE/L). 2020 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/92889/1/ChuaLeeSuan2020_SolventPartitionforTerpenoidRichFraction.pdf Mohd. Ismail, Nurul Izzati and Lee, Suan Chua (2020) Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia. In: Proceedings of the Third International Conference on Separation Technology 2020 (ICoST 2020), 30 December 2020, Johor Bahru, Virtual. http://dx.doi.org/10.2991/aer.k.201229.009
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Mohd. Ismail, Nurul Izzati
Lee, Suan Chua
Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
description The root of Eurycoma longifolia or locally called as Tongkat Ali contains numerous health benefits, mainly due to the bioactive compounds. The main compound of interest is from the group of quassinoids which is also known as degraded triterpenoids such as eurycomanone, eurycomalactone, longilactone, pasakbumin B and pasakbumin C. Quassinoids or degraded triterpenoids were reported to possess anti-malarial, anti-diabetic, anti-bacterial and anti-cancer effects. Therefore, it is important to concentrate terpenoids rich fraction from the crude extract of E. longifolia roots to enhance the reported bioactivities. The present study was carried out to determine the suitable solvent in concentrating terpenoids from the crude extract of E. longifolia roots. Organic solvents such as chloroform, butanol and ethyl acetate were selected to maximally recover terpenoids based on the principle of liquid-liquid extraction. The quality of the fractions was compared and analysed for the phytochemical composition. The results showed all organic fractions contained higher total terpenoid content than its aqueous counterpart. The chloroform fraction exhibited the highest yield of mass fraction (72.90 ± 0.15%) and the highest total terpenoid content (0.47 ± 0.01 mg OAE/L).
format Conference or Workshop Item
author Mohd. Ismail, Nurul Izzati
Lee, Suan Chua
author_facet Mohd. Ismail, Nurul Izzati
Lee, Suan Chua
author_sort Mohd. Ismail, Nurul Izzati
title Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
title_short Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
title_full Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
title_fullStr Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
title_full_unstemmed Solvent partition for terpenoid rich fraction from crude extract of Eurycoma longifolia
title_sort solvent partition for terpenoid rich fraction from crude extract of eurycoma longifolia
publishDate 2020
url http://eprints.utm.my/id/eprint/92889/1/ChuaLeeSuan2020_SolventPartitionforTerpenoidRichFraction.pdf
http://eprints.utm.my/id/eprint/92889/
http://dx.doi.org/10.2991/aer.k.201229.009
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score 13.222552