β-Sheet Containment by Flanking Prolines: Molecular Dynamic Simulations of the Inhibition of β-Sheet Elongation by Proline Residues in Human Prion Protein

Previous molecular dynamic simulations have reported elongation of the existing β-sheet in prion proteins. Detailed examination has shown that these elongations do not extend beyond the proline residues flanking these β-sheets. In addition, proline has also been suggested to possess a possible str...

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Bibliographic Details
Main Authors: Shamsir, Mohd. S., Dalby, Andrew
Format: Article
Published: Elsevier 2007
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Online Access:http://eprints.utm.my/id/eprint/9258/
https://doi.org/10.1529/biophysj.106.092320
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