Study on molecular docking of red betel (Piper crocatum Ruiz & Pav.) active compound and tamoxifen drug as an inhibitor of estrogen receptor-α (ER-α) that plays a role in breast cancer

• Main Authors: Maslikah, Siti Imroatul, Lestari, Sri Rahayu, Handayani, Nursasi, Nik Malek, Nik Ahmad Nizam, Jemon, Khairunadwa, Amalia, Atikah, Afifah, Solichatul
• Format: Conference or Workshop Item
• Language: English
• Published: 2020
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/89970/1/NikAhmadNizam2020_StudyonMolecularDockingofRedBetel.pdf; http://eprints.utm.my/id/eprint/89970/; http://dx.doi.org/10.1063/5.0002556

Breast cancer is the second leading cause of death due to cancer among women. The most common trigger of cancer is an excessive expression of Estrogen Receptor-α (ER-α) which plays a significant role in the growth, development, and pathophysiology of the breast. Tamoxifen is one of Selective Estroge...