Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds
Bone tissue scaffolds require appropriate properties conducive for new tissue growth. In this study, we prepared a novel electrospun nanofiber scaffold using polyurethane (PU), rosemary (RM) oil and copper sulphate (CuSO4) respectively. The properties of the developed membranes were established thro...
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my.utm.875882020-11-30T09:04:10Z http://eprints.utm.my/id/eprint/87588/ Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds Jaganathan, S. K. Mani, Mohan Prasath Ayyar, M. Rathanasamy, Rajasekar Q Science (General) Bone tissue scaffolds require appropriate properties conducive for new tissue growth. In this study, we prepared a novel electrospun nanofiber scaffold using polyurethane (PU), rosemary (RM) oil and copper sulphate (CuSO4) respectively. The properties of the developed membranes were established through scanning electron microscopy (FESEM), atomic force microscopy (AFM), attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR), thermal gravimetric analysis (TGA), contact angle and mechanical testing. Further, blood compatibility and cytocompatibility assay were carried out to evaluate their biological responses. The developed composites rendered appropriate surface morphology with tailor made wettability and roughness. Composites with engineered physicochemical properties improved the blood and cytocompatible properties which can be potentially exploited for bone tissue engineering applications. Elsevier Ltd 2019-09 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/87588/1/SaravanaKumarJaganathan2019_BiomimeticElectrospunPolyurethaneMatrixComposites.pdf Jaganathan, S. K. and Mani, Mohan Prasath and Ayyar, M. and Rathanasamy, Rajasekar (2019) Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds. Polymer Testing, 78 . p. 105955. ISSN 0142-9418 http://dx.doi.org/10.1016/j.polymertesting.2019.105955 |
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Q Science (General) Jaganathan, S. K. Mani, Mohan Prasath Ayyar, M. Rathanasamy, Rajasekar Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
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Bone tissue scaffolds require appropriate properties conducive for new tissue growth. In this study, we prepared a novel electrospun nanofiber scaffold using polyurethane (PU), rosemary (RM) oil and copper sulphate (CuSO4) respectively. The properties of the developed membranes were established through scanning electron microscopy (FESEM), atomic force microscopy (AFM), attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR), thermal gravimetric analysis (TGA), contact angle and mechanical testing. Further, blood compatibility and cytocompatibility assay were carried out to evaluate their biological responses. The developed composites rendered appropriate surface morphology with tailor made wettability and roughness. Composites with engineered physicochemical properties improved the blood and cytocompatible properties which can be potentially exploited for bone tissue engineering applications. |
format |
Article |
author |
Jaganathan, S. K. Mani, Mohan Prasath Ayyar, M. Rathanasamy, Rajasekar |
author_facet |
Jaganathan, S. K. Mani, Mohan Prasath Ayyar, M. Rathanasamy, Rajasekar |
author_sort |
Jaganathan, S. K. |
title |
Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
title_short |
Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
title_full |
Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
title_fullStr |
Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
title_full_unstemmed |
Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
title_sort |
biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds |
publisher |
Elsevier Ltd |
publishDate |
2019 |
url |
http://eprints.utm.my/id/eprint/87588/1/SaravanaKumarJaganathan2019_BiomimeticElectrospunPolyurethaneMatrixComposites.pdf http://eprints.utm.my/id/eprint/87588/ http://dx.doi.org/10.1016/j.polymertesting.2019.105955 |
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1685578959020883968 |
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13.18916 |