Generalisations of DNA Splicing Systems with One Palindromic Restriction Enzyme

• Main Authors: Fong, Wan Heng, Ismail, Nurul Izzaty
• Format: Article
• Language: English
• Published: Penerbit UTM Press 2018
• Subjects: QA Mathematics
• Online Access: http://eprints.utm.my/id/eprint/84856/1/FongWanHeng2018_GeneralisationsofDNASplicingSystems.pdf; http://eprints.utm.my/id/eprint/84856/; http://dx.doi.org/10.11113/matematika.v34.n1.1011

In DNA splicing system, the potential effect of sets of restriction enzymes and a ligase that allow DNA molecules to be cleaved and re-associated to produce further molecules is modelled mathematically. This modelling is done in the framework of formal language theory, in which the nitrogen bases, nucleotides and restriction sites are modelled as alphabets, strings and rules respectively. The molecules resulting from a splicing system is depicted as the splicing language. In this research, the splicing language resulting from DNA splicing systems with one palindromic restriction enzyme for one and two (non-overlapping) cutting sites are generalised as regular expressions.