Synthesis, spectral characterization, crystal and molecular structure studies of 5-(5‑bromo‑2-thienyl)-1-(phenyl)-3-phenyl-2-pyrazoline

• Main Authors: Naveen, S., Ahmad, Noor Aisyah, Urs, M. V. Deepa, Lingegowda, N. S., Jamalis, Joazaizulfazli, Reddy, Kakarla Raghava, Lokanath, N. K.
• Format: Article
• Published: Elsevier B.V. 2018
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/84360/; https://doi.org/10.1016/j.cdc.2018.08.008

The title compound 5-(5‑bromo‑2-thienyl)-1-(phenyl)-3-phenyl-2-pyrazoline has been synthesized and the structure was characterized using 1H NMR, 13C NMR, IR techniques and finally the structure was confirmed by X-ray diffraction studies. The IR spectrum of 5-(5‑bromo‑2-thienyl)-1-(phenyl)-3-phenyl-2-pyrazoline showed that absorptions in at 3064 cm−1 for C-H sp2, 2907 cm−1 for C-H sp3, 1561 and 1591 for C = C aromatic bond stretchings. The 1H and 13C NMR spectra of revealed the existence of all protons and carbons for the structure. The X-ray crystal structure studies revealed that pyrazoline ring in the structure is in an envelope conformation. The structure possesses a chiral centre at C5 with R conformation. The thiophene ring in the structure is affected by π conjugation.