Flavonoids mediated 'Green' nanomaterials: A novel nanomedicine system to treat various diseases - Current trends and future perspective

• Main Authors: Sathishkumar, P., Gu, F. L., Zhan, Q., Palvannan, T., Mohd. Yusoff, A. R.
• Format: Article
• Language: English
• Published: Elsevier B.V. 2018
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/83961/1/PalanivelSathishkumar2018_FlavonoidsMediatedGreenNanomaterials.pdf; http://eprints.utm.my/id/eprint/83961/; http://dx.doi.org/10.1016/j.matlet.2017.08.078

Nanomedicine utilizes biocompatible nanomaterials for therapeutic purposes to treat various diseases. Flavonoids present in the plant materials act as both reducing and electrostatic stabilizing agents for the ‘Green’ synthesis of metal nanomaterials. Further, these nanomaterials are effectively used to treat various cancer cells and pathogenic microbes. The experimental approach for flavonoids-mediated nanomaterial (FMN) synthesis is simple, rapid, cost-effective and reproducible. However, the detailed reports on synthesis, mechanism, and in vivo application of FMN are very limited in literatures. Thus, this focused review will definitely help researchers who are working on biocompatible nanomaterial synthesis and application in biomedical sector. Further, this is the first review to discuss the significance, mechanisms, and future trends of FMN. The FMN and their dual function as both nano-carrier and nano-drug in various biomedical sectors might be a hot research topic in upcoming days.