Tertiary structure prediction of bromelain from Ananas Comosus using comparative modelling method
Bromelain is a general name for a family of sulfhydryl which can be found in the proteolytic enzyme group from pineapples (Ananas Comosus). This study focuses on the prediction of three dimensional structures (3D) of stem bromelain using the method of comparative modelling. The amino acid sequence o...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Inst Advanced Science Extension
2017
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| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/77285/1/FatahiyaMohamedTap2017_TertiaryStructurePredictionofBromelain.pdf http://eprints.utm.my/id/eprint/77285/ |
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| Summary: | Bromelain is a general name for a family of sulfhydryl which can be found in the proteolytic enzyme group from pineapples (Ananas Comosus). This study focuses on the prediction of three dimensional structures (3D) of stem bromelain using the method of comparative modelling. The amino acid sequence of bromelain was obtained from the NCBI database was used as a tool to search for proteins with known 3D structures related to the target sequence. Suitable template was chosen based on >30% sequence similarity and lowest e-value. Based on these criteria, 1YAL was selected as the best template with 55% of sequence similarity and 9x10(-52) of e-value. (c) 2017 The Authors. Published by IASE. |
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