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Lactones and flavonoids isolated from the leaves of globimetula braunii

The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAcsoluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6-dihydropyran-2-one (dod...

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Main Authors: Ja'afar, M. K., Jamil, S., Basar, N., Bakar, M. B., Sarker, S. D., Flanagan, K. J., Senge, M. O.
Format: Article
Published: Natural Product Incorporation 2017
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/77118/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030706380&partnerID=40&md5=d07d1df4323e29a13ff45706dde2c95d
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spelling my.utm.771182018-04-30T14:43:18Z http://eprints.utm.my/id/eprint/77118/ Lactones and flavonoids isolated from the leaves of globimetula braunii Ja'afar, M. K. Jamil, S. Basar, N. Bakar, M. B. Sarker, S. D. Flanagan, K. J. Senge, M. O. QD Chemistry The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAcsoluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6-dihydropyran-2-one (dodoneine) 1 and (1R,5S,7S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of compound 1 was confirmed by X-ray analysis. Natural Product Incorporation 2017 Article PeerReviewed Ja'afar, M. K. and Jamil, S. and Basar, N. and Bakar, M. B. and Sarker, S. D. and Flanagan, K. J. and Senge, M. O. (2017) Lactones and flavonoids isolated from the leaves of globimetula braunii. Natural Product Communications, 12 (9). pp. 1455-1458. ISSN 1934-578X https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030706380&partnerID=40&md5=d07d1df4323e29a13ff45706dde2c95d
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Ja'afar, M. K.
Jamil, S.
Basar, N.
Bakar, M. B.
Sarker, S. D.
Flanagan, K. J.
Senge, M. O.
Lactones and flavonoids isolated from the leaves of globimetula braunii
description The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAcsoluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6-dihydropyran-2-one (dodoneine) 1 and (1R,5S,7S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of compound 1 was confirmed by X-ray analysis.
format Article
author Ja'afar, M. K.
Jamil, S.
Basar, N.
Bakar, M. B.
Sarker, S. D.
Flanagan, K. J.
Senge, M. O.
author_facet Ja'afar, M. K.
Jamil, S.
Basar, N.
Bakar, M. B.
Sarker, S. D.
Flanagan, K. J.
Senge, M. O.
author_sort Ja'afar, M. K.
title Lactones and flavonoids isolated from the leaves of globimetula braunii
title_short Lactones and flavonoids isolated from the leaves of globimetula braunii
title_full Lactones and flavonoids isolated from the leaves of globimetula braunii
title_fullStr Lactones and flavonoids isolated from the leaves of globimetula braunii
title_full_unstemmed Lactones and flavonoids isolated from the leaves of globimetula braunii
title_sort lactones and flavonoids isolated from the leaves of globimetula braunii
publisher Natural Product Incorporation
publishDate 2017
url http://eprints.utm.my/id/eprint/77118/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030706380&partnerID=40&md5=d07d1df4323e29a13ff45706dde2c95d
_version_ 1643657503353864192
score 13.187197

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