A model of the mechanical degradation of foam replicated scaffolds
Tissue engineering scaffolds are implants that actively support tissue growth whilst providing mechanical support. For optimum functionality, they are designed to slowly dissolve in vivo so that no foreign material remains permanently implanted inside the body. The current study uses a simple degrad...
Saved in:
Main Authors: | , , , , |
---|---|
Format: | Article |
Published: |
Springer New York LLC
2016
|
Subjects: | |
Online Access: | http://eprints.utm.my/id/eprint/72745/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955672692&doi=10.1007%2fs10853-015-9701-x&partnerID=40&md5=1c4d31a6f0f823aa2a9a2373054162af |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my.utm.72745 |
---|---|
record_format |
eprints |
spelling |
my.utm.727452017-11-27T09:02:13Z http://eprints.utm.my/id/eprint/72745/ A model of the mechanical degradation of foam replicated scaffolds Sulong, Mohd. Ayub Belova, I. V. Boccaccini, A. R. Murch, G. E. Fiedler, T. TJ Mechanical engineering and machinery Tissue engineering scaffolds are implants that actively support tissue growth whilst providing mechanical support. For optimum functionality, they are designed to slowly dissolve in vivo so that no foreign material remains permanently implanted inside the body. The current study uses a simple degradation model that estimates the change of scaffold geometry due to surface erosion. This model is applied on scaffolds that have been manufactured using the foam replication method. In order to capture their complex geometry, micro-computed tomography scans of samples are obtained. Their change in geometry and degradation of mechanical properties is evaluated using computational analysis. The present investigation found that the mechanical properties such as the quasi-elastic gradient, 0.2 % offset yield stress and the plateau stress are decreased systematically over a 10-week period of immersion time. Deformation analysis on the titania foam scaffold is performed by means of the deformed model obtained from finite element calculations. Springer New York LLC 2016 Article PeerReviewed Sulong, Mohd. Ayub and Belova, I. V. and Boccaccini, A. R. and Murch, G. E. and Fiedler, T. (2016) A model of the mechanical degradation of foam replicated scaffolds. Journal of Materials Science, 51 (8). pp. 3824-3835. ISSN 0022-2461 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955672692&doi=10.1007%2fs10853-015-9701-x&partnerID=40&md5=1c4d31a6f0f823aa2a9a2373054162af |
institution |
Universiti Teknologi Malaysia |
building |
UTM Library |
collection |
Institutional Repository |
continent |
Asia |
country |
Malaysia |
content_provider |
Universiti Teknologi Malaysia |
content_source |
UTM Institutional Repository |
url_provider |
http://eprints.utm.my/ |
topic |
TJ Mechanical engineering and machinery |
spellingShingle |
TJ Mechanical engineering and machinery Sulong, Mohd. Ayub Belova, I. V. Boccaccini, A. R. Murch, G. E. Fiedler, T. A model of the mechanical degradation of foam replicated scaffolds |
description |
Tissue engineering scaffolds are implants that actively support tissue growth whilst providing mechanical support. For optimum functionality, they are designed to slowly dissolve in vivo so that no foreign material remains permanently implanted inside the body. The current study uses a simple degradation model that estimates the change of scaffold geometry due to surface erosion. This model is applied on scaffolds that have been manufactured using the foam replication method. In order to capture their complex geometry, micro-computed tomography scans of samples are obtained. Their change in geometry and degradation of mechanical properties is evaluated using computational analysis. The present investigation found that the mechanical properties such as the quasi-elastic gradient, 0.2 % offset yield stress and the plateau stress are decreased systematically over a 10-week period of immersion time. Deformation analysis on the titania foam scaffold is performed by means of the deformed model obtained from finite element calculations. |
format |
Article |
author |
Sulong, Mohd. Ayub Belova, I. V. Boccaccini, A. R. Murch, G. E. Fiedler, T. |
author_facet |
Sulong, Mohd. Ayub Belova, I. V. Boccaccini, A. R. Murch, G. E. Fiedler, T. |
author_sort |
Sulong, Mohd. Ayub |
title |
A model of the mechanical degradation of foam replicated scaffolds |
title_short |
A model of the mechanical degradation of foam replicated scaffolds |
title_full |
A model of the mechanical degradation of foam replicated scaffolds |
title_fullStr |
A model of the mechanical degradation of foam replicated scaffolds |
title_full_unstemmed |
A model of the mechanical degradation of foam replicated scaffolds |
title_sort |
model of the mechanical degradation of foam replicated scaffolds |
publisher |
Springer New York LLC |
publishDate |
2016 |
url |
http://eprints.utm.my/id/eprint/72745/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955672692&doi=10.1007%2fs10853-015-9701-x&partnerID=40&md5=1c4d31a6f0f823aa2a9a2373054162af |
_version_ |
1643656510601953280 |
score |
13.214268 |