Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities
Swietenia mahagoni seeds have been used as folk medicine for a treatment of hypertension, malaria and diabetes. This research was conducted to obtain extracts from the Swietenia mahagoni using supercritical fluid extraction (SFE) with pure CO2 solvent, in order to evaluate the high- pressure method...
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my.utm.627252017-11-01T04:17:09Z http://eprints.utm.my/id/eprint/62725/ Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities Hartati, Hartati Md. Salleh, Liza Ismail, Ahmad Ramdan Che Yunus, Mohd. Azizi Abd. Aziz, Azila TP Chemical technology Swietenia mahagoni seeds have been used as folk medicine for a treatment of hypertension, malaria and diabetes. This research was conducted to obtain extracts from the Swietenia mahagoni using supercritical fluid extraction (SFE) with pure CO2 solvent, in order to evaluate the high- pressure method in terms of process yield and biological activity. The various conditions namely flow rate of CO2 were set up at 2, 3, and 4 ml/min; at constant pressures (P) and temperature (T). The sample extracts obtained by SFE with CO2 flow rate of 4 ml/min showed the highest percentage yield (19.67%) compared to the others. The antioxidant potential of the extracts was evaluated by the DPPH method and Folin- Ciocalteu method. The solvent flow rate of 2 ml/min gave the lowest percentage of yield, but good results in antioxidant activity and total phenolic content. The antimicrobial activity of the extracts against Gram-positive (Bacillus subtilis, Staphylococcus aureus) and Gram-negative (Escherichia coli) was evaluated based on the inhibition zone using disc diffusion assay. These results ensured that Swietenia mahagoni seed extract had inhibitory effects on the growth of Bacillus subtilis, Staphylococcus aureus and Escherichia coli at concentration of 100 mg/ml. Penerbit UTM Press 2014 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/62725/1/LizaMdSalleh2014_SupercriticalFluidExtractionofSwietenia.pdf Hartati, Hartati and Md. Salleh, Liza and Ismail, Ahmad Ramdan and Che Yunus, Mohd. Azizi and Abd. Aziz, Azila (2014) Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities. Jurnal Teknologi (Sciences and Engineering), 67 (4). pp. 59-62. ISSN 2180-3722 http://dx.doi.org/10.11113/jt.v67.2799 DOI:10.11113/jt.v67.2799 |
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TP Chemical technology Hartati, Hartati Md. Salleh, Liza Ismail, Ahmad Ramdan Che Yunus, Mohd. Azizi Abd. Aziz, Azila Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
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Swietenia mahagoni seeds have been used as folk medicine for a treatment of hypertension, malaria and diabetes. This research was conducted to obtain extracts from the Swietenia mahagoni using supercritical fluid extraction (SFE) with pure CO2 solvent, in order to evaluate the high- pressure method in terms of process yield and biological activity. The various conditions namely flow rate of CO2 were set up at 2, 3, and 4 ml/min; at constant pressures (P) and temperature (T). The sample extracts obtained by SFE with CO2 flow rate of 4 ml/min showed the highest percentage yield (19.67%) compared to the others. The antioxidant potential of the extracts was evaluated by the DPPH method and Folin- Ciocalteu method. The solvent flow rate of 2 ml/min gave the lowest percentage of yield, but good results in antioxidant activity and total phenolic content. The antimicrobial activity of the extracts against Gram-positive (Bacillus subtilis, Staphylococcus aureus) and Gram-negative (Escherichia coli) was evaluated based on the inhibition zone using disc diffusion assay. These results ensured that Swietenia mahagoni seed extract had inhibitory effects on the growth of Bacillus subtilis, Staphylococcus aureus and Escherichia coli at concentration of 100 mg/ml. |
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Article |
author |
Hartati, Hartati Md. Salleh, Liza Ismail, Ahmad Ramdan Che Yunus, Mohd. Azizi Abd. Aziz, Azila |
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Hartati, Hartati Md. Salleh, Liza Ismail, Ahmad Ramdan Che Yunus, Mohd. Azizi Abd. Aziz, Azila |
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Hartati, Hartati |
title |
Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
title_short |
Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
title_full |
Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
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Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
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Supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
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supercritical fluid extraction of swietenia mahagoni seed: antioxidant and antimicrobial activities |
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Penerbit UTM Press |
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2014 |
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http://eprints.utm.my/id/eprint/62725/1/LizaMdSalleh2014_SupercriticalFluidExtractionofSwietenia.pdf http://eprints.utm.my/id/eprint/62725/ http://dx.doi.org/10.11113/jt.v67.2799 |
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