SWCNT-based biosensor modelling for ph detection

• Main Authors: Kiani, Mohammad Javad, Abdul Razak, Mohd. Azhar, Che Harun, Fauzan Khairi, Ahmadi, Mohammad Taghi Aghi, Rahmani, Meisam
• Format: Article
• Published: Hindawi Publishing Corporation 2015
• Subjects: TK Electrical engineering. Electronics Nuclear engineering
• Online Access: http://eprints.utm.my/id/eprint/58855/; http://dx.doi.org/10.1155/2015/721251

Different forms of CNT delivery have been discovered with several biomedical functions during past decades. The mechanisms of the cellular uptake of CNTs are mainly maintained due to the chemical nature, the cell type, and the features of the molecules, which are used to functionalize the nanotube exterior. Since single-wall carbon Nanotube (SWCNT) has unique chemical and physical properties, it is a great applicant for pH sensing. In addition, ion sensitive FET (ISFET) base on nanostructured SWCNT have covered a new method to help genetic investigators restructure metabolic pathways in cells, recognize the progression of disease, and expand diagnostics and therapeutics. Particularly, because PH sensing is very crucial for the constancy of enzymes, it is essential to extend the cost efficient types of this sensing. In this research, the conductance changes of the CNT-based ISFET device with different pH values can be modelled by ion concentration of the solution. In addition, the electrical current of channel is imagined as a function of pH levels, which can be controlled by a control factor (a). Thus, ISFET based nanostructured SWCNT is proposed focusing on the area of electrical detection of hydrogen ions of the electrolyte membrane. Besides, electrical detection of hydrogen ion applications is suggested to be used by modelling the delivery of SWCNT sheets. In the end, after comparing the proposed model and experimental data, it has been reported that there is a good compatibility between them.