Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix

• Main Authors: Jusoh, Norhana, Oh, Soo Jung, Kim, Su Dong, Kim, Jang Ho, Jeon, Noo li
• Format: Article
• Published: Royal Society of Chemistry Funding details 2015
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/58546/; http://dx.doi.org/10.1039/c5lc00698h

Current in vitro systems mimicking bone tissues fail to fully integrate the three-dimensional (3D) microvasculature and bone tissue microenvironments, decreasing their similarity to in vivo conditions. Here, we propose 3D microvascular networks in a hydroxyapatite (HA)-incorporated extracellular mat...