Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells

• Main Authors: Tahir, Analhuda Abdullah, Abdul Sani, Nur Fathiah, Murad, Noor Azian, Makpol, Suzana, Wan Ngah, Wan Zurinah, Mohd. Yusof, Yasmin Anum
• Format: Article
• Published: BioMed Central Ltd. 2015
• Subjects: Q Science (General); TA Engineering (General). Civil engineering (General)
• Online Access: http://eprints.utm.my/id/eprint/58081/; http://dx.doi.org/10.1186/s12937-015-0015-2

Background: The interconnected Ras/ERK and PI3K/AKT pathways play a central role in colorectal tumorigenesis, and they are targets for elucidating mechanisms involved in attempts to induce colon cancer cell death. Both ginger (Zingiber officinale) and honey have been shown to exhibit anti-tumor and...