Arterial hemodynamics in patent ductus arteriosus stenting

• Main Author: Jamalruhanordin, Fara Lyana
• Format: Thesis
• Language: English
• Published: 2015
• Subjects: R Medicine (General)
• Online Access: http://eprints.utm.my/id/eprint/53856/1/FaraLyanaJamalruhanordinMFBME2015.pdf; http://eprints.utm.my/id/eprint/53856/; http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:85894

Cyanotic congenital heart disease (CHD) is the condition when insufficient blood transported throughout the whole body due to anomalies of blood vessels or heart. Hence, the procedure of maintaing the patency of ductus arteriosus were introduced where the stent is implanted at ductus arteriosus that should be closed naturally within 48 hours after the birth. The main purpose of this study is to investigate the hemodyamic effect of patent ductus arteriosus (PDA) after different types of stent design were implanted. Three different types of commercial stent design were used in this study: Closed Cell V stent, Palmaz-Schatz stent and Type One stent. The hemodynamic effect were investigated numerically via computational fluid dynamics by using ANSYS 14.0 software. Three hemodynamics variables were analysed in this study which are wall shear stress (WSS), oscillatory shear index (OSI) and relative residence time (RRT). Each stent affect the hemodynamic within PDA differently. The higher percentage of TAWSS exposed in range of 0.5 Pa to 2 Pa is better shown by Closed Cell V stent with 25.4%. Type One stent shown a good result in OSI which has high percentages exposed below 0.2 with the value of 34%. Palmaz-Schatz stent present a preferable results in both WSS low, 1.2% (low the better) and RRT within range of 10 Pa^-1 at 97.7%. Thus, this study can be useful in stent selection for PDA stenting.