Amelioration of mitochondrial dysfunction-induced insulin resistance in differentiated 3T3-L1 adipocytes via inhibition of NF-κB pathways

• Main Authors: Abu Bakar, Mohamad Hafizi, Sarmidi, Mohamad Roji, Cheng, Kian Kai, Huri, Hasniza Zaman, Ya’akob, Harisun
• Format: Article
• Language: English
• Published: MDPI AG 2014
• Subjects: QP Physiology
• Online Access: http://eprints.utm.my/id/eprint/51756/1/MohamadHafiziAbuBakar2014_AMeliorationOfMitochondrialDysfunction.pdf; http://eprints.utm.my/id/eprint/51756/; http://dx.doi.org/10.3390/ijms151222227

A growing body of evidence suggests that activation of nuclear factor kappa B (NF-κB) signaling pathways is among the inflammatory mechanism involved in the development of insulin resistance and chronic low-grade inflammation in adipose tissues derived from obese animal and human subjects. Neverthel...