Conformational transitions of proteins engaged in dna double-strand break repair, analysed by trytophan flourescence emission and fret
We analysed protein–DNA and protein–protein interactions relevant to the repair of DNA DSBs (double-strand breaks) by NHEJ (non-homologous end-joining). Conformational transitions in mammalian DNA ligases III (LigIII) and IV (LigIV), as well as in PARP-1 [poly(ADP-ribose) polymerase-1], were analyse...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
Biochemical Society
2012
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| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/46731/ http://dx.doi.org/10.1042/BJ20112151 |
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