Integrated dual nanoprobe-microfluidic system for single cell penetration
This paper presents the results in single cell intracellular penetration using the integrated dual nanoprobe-microfluidic system. Current technique for single cell penetration is using a manual controlled nanomanipulator which been attached with a nanoprobe. Due to this, successful single cell penet...
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my.utm.380932017-09-26T07:05:43Z http://eprints.utm.my/id/eprint/38093/ Integrated dual nanoprobe-microfluidic system for single cell penetration Mat Sulaiman, Abdul Hafiz Ahmad, Mohd. Ridzuan TK Electrical engineering. Electronics Nuclear engineering This paper presents the results in single cell intracellular penetration using the integrated dual nanoprobe-microfluidic system. Current technique for single cell penetration is using a manual controlled nanomanipulator which been attached with a nanoprobe. Due to this, successful single cell penetration depends on the operator skills. We proposed an integrated dual nanoprobe-microfluidic system. The system was being developed to reduce the requirement for skilled operator in single cell electrical measurement. We tested the system function for single cell penetration via finite element simulation. Based on the results, the single cell can be penetrated at fluid velocity of 5.3 μm/s. Currently, the developed system is suitable for cell viability detection application. However, this system has the potential to be used in single cell thermal measurement, single cell drug delivery, and early disease diagnosis. 2013 Conference or Workshop Item PeerReviewed Mat Sulaiman, Abdul Hafiz and Ahmad, Mohd. Ridzuan (2013) Integrated dual nanoprobe-microfluidic system for single cell penetration. In: 2013 IEEE International Conference on Control System, Computing and Engineering (ICCSCE 2013). |
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TK Electrical engineering. Electronics Nuclear engineering Mat Sulaiman, Abdul Hafiz Ahmad, Mohd. Ridzuan Integrated dual nanoprobe-microfluidic system for single cell penetration |
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This paper presents the results in single cell intracellular penetration using the integrated dual nanoprobe-microfluidic system. Current technique for single cell penetration is using a manual controlled nanomanipulator which been attached with a nanoprobe. Due to this, successful single cell penetration depends on the operator skills. We proposed an integrated dual nanoprobe-microfluidic system. The system was being developed to reduce the requirement for skilled operator in single cell electrical measurement. We tested the system function for single cell penetration via finite element simulation. Based on the results, the single cell can be penetrated at fluid velocity of 5.3 μm/s. Currently, the developed system is suitable for cell viability detection application. However, this system has the potential to be used in single cell thermal measurement, single cell drug delivery, and early disease diagnosis. |
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Conference or Workshop Item |
author |
Mat Sulaiman, Abdul Hafiz Ahmad, Mohd. Ridzuan |
author_facet |
Mat Sulaiman, Abdul Hafiz Ahmad, Mohd. Ridzuan |
author_sort |
Mat Sulaiman, Abdul Hafiz |
title |
Integrated dual nanoprobe-microfluidic system for single cell penetration |
title_short |
Integrated dual nanoprobe-microfluidic system for single cell penetration |
title_full |
Integrated dual nanoprobe-microfluidic system for single cell penetration |
title_fullStr |
Integrated dual nanoprobe-microfluidic system for single cell penetration |
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Integrated dual nanoprobe-microfluidic system for single cell penetration |
title_sort |
integrated dual nanoprobe-microfluidic system for single cell penetration |
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2013 |
url |
http://eprints.utm.my/id/eprint/38093/ |
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1643650218814603264 |
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13.160551 |