Protein refolding in an oscillatory-flow-mixing reactor
We demonstrate that an oscillatory flow-mixing reactor (OFMR) operating in fed-batch mode is viable for industrial protein refolding. OFMR offers the advantage of uniform, controllable, and scalable mixing. Denatured lysozyme (15 mg/ml, in 8 M guanidine hydrochloride (GuHCl) or 8 M urea, and 32 mM...
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Main Authors: | Lee, C. T., Middelberg, Anton |
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Format: | Conference or Workshop Item |
Published: |
2001
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Online Access: | http://eprints.utm.my/id/eprint/3117/ |
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