Optimization of supercritical carbon dioxide extraction of bioactive flavonoid compounds from spearmint (Mentha spicata L.) leaves by using response surface methodology

• Main Authors: Bimakr, Mandana, Abdul Rahman, Russly, Ganjloo, Ali, Taip, Farah Saleena, Md. Salleh, Liza, Sarker, Md Zaidul Islam
• Format: Article
• Published: Springer 2011
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/id/eprint/29553/; http://dx.doi.org/10.1007/s11947-010-0504-4

The bioactive flavonoid compounds of spearmint (Mentha spicata L.) leaves were obtained by using supercritical carbon dioxide (SC-CO2) extraction. Extraction was carried out according to face-centred central composite design, and independent variables were pressure (100, 200 and 300 bar), temperatur...