Synthesis of 4’,5,7-trihydroxyflavanone and 3’,4’,5,7-tetrahydroxyflavanone and antioxidant activity

• Main Authors: Ahmad, Farediah, Mohamed Adib, Adiana, Idris , Muhamad Sum
• Format: Article
• Language: English; English
• Published: ibnu Sina Institute for Fundamental Science Studies, Universiti Teknologi Malaysia 2010
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/25999/3/FarediahAhmad2010_Synthesisof4%E2%80%99%2C5%2C7-trihydroxyflavanoneand3%E2%80%99%2C4%E2%80%99%2C5%2C7-tetrahydroxyflavanone.pdf; http://eprints.utm.my/id/eprint/25999/2/83; http://eprints.utm.my/id/eprint/25999/; http://mjfas.ibnusina.utm.my/index.php/jfs/article/view/146; http://mjfas.ibnusina.utm.my/index.php/jfs/article/view/146/83

Natural flavonoid, namely 4’,5,7-trihydroxyflavanone and 3’,4’,5,7-tetrahydroxyflavanone were synthesised via its chalcone. The initial step was to synthesize derivatives of 2-hydroxyacetophenone and benzaldehyde by protecting the phenolic hydroxyl groups. The respective chalcone was synthesised by...