Synergistic effects of combined cisplatin and clinacanthus nutans extract on triple negative breast cancer cells.

• Main Authors: Abu Bakar, Nur Fitriyani Afiqah, Yeo, Zhin Leng, Hussin, Faisal, Madhavan, Priya, Lim, Vuanghao, Jemon, Khairunadwa, Prabhakaran, Praseetha
• Format: Article
• Language: English
• Published: Elsevier B.V. 2023
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/107178/1/NurFitriyaniAfiqahAbuBakar2023_SynergisticEffectsofCombinedCisplatinandClinacanthusExtract.pdf; http://eprints.utm.my/107178/; http://dx.doi.org/10.1016/j.jtumed.2023.04.003

Objective: Triple negative breast cancer (TNBC) is the most invasive breast cancer subtype enriched with cancer stem cells. TNBCs do not express estrogen, progesterone, or human epidermal growth factor receptor 2 (HER2) receptors, making them difficult to be targeted by existing chemotherapy treatme...