A new solubility model for competing effects of three solvents: water, ethanol, and supercritical carbon dioxide

• Main Authors: Nicky Rahmana Putra, Nicky Rahmana Putra, Dwila Nur Rizkiyah, Dwila Nur Rizkiyah, Idham, Zuhaili, Jumakir, Jumakir, Waluyo, Waluyo, Mohd. Faizal, Azrul Nurfaiz, Ahmad Zaini, Muhammad Abbas, Che Yunus, Mohd. Azizi
• Format: Article
• Published: Taylor and Francis Group 2022
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/104111/; http://dx.doi.org/10.1080/01496395.2022.2045317

This study aims to develop a new semi-empirical model to fit solute solubility in a mixture of solvents, viz. supercritical carbon dioxide, ethanol, and water, as well as to evaluate the effects of competing solvents on solubility. Therefore, the model was assessed by fitting the published solubility data and comparing it with the established semi-empirical models. The findings revealed that the new model gave the highest coefficient of determination, R2 of 0.96 and had the lowest AARD (i.e., 3.88%), compared to other models. To conclude, the new model is feasible in determining three solvents’ solvation effects in one system.