In vitro antioxidant and anticholinesterase activities of ethanolic turmeric crude extract

• Main Authors: Abbas, S., Latif, S. M., Muhamad, Ida Idayu, Hesan, M. A., Kormin, F.
• Format: Article
• Language: English
• Published: Rynnye Lyan Resources 2022
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/104010/1/IdaIdayuMuhamad2022_InVitroAntioxidantandAnticholinesteraseActivities.pdf; http://eprints.utm.my/104010/; http://dx.doi.org/10.26656/fr.2017.6(4).101

This study was aimed at exploring the antioxidant and anticholinesterase effect of ethanolic turmeric crude extract. The antioxidant activity was determined by using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging activity, (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) (ABTS) and ferric reducing antioxidant power (FRAP) values. Ethanolic crude extract of turmeric showed good antioxidant and anticholinesterase activities (% I), the activity was, 80.2±1.30%, 75.6±1.23% and 10.43±0.28% for ABTS, DPPH and FRAP, respectively, and 69.0±1.85% and 70.5±1.11% for AChE and BChE, respectively. However, the maximum% I for ABTS, DPPH and FRAP, that is, 87.2±1.34%, 86.0±1.59% and 19.36±0.37 µg FSE, respectively, were shown by positive control ascorbic acid, and for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition, 86.69±1.24 and 89.3±1.01%, respectively, by galanthamine. Turmeric provides a potential natural source of bioactive compounds and is valuable to human health.