Streptomyces sp. ADR1, strain producing beta- and gamma-rubromycin antibiotics, isolated from Algerian Sahara Desert

• Main Authors: Boumehira, Ali Zineddine, Kirby, Bronywn, Trindade, Marla, Hacène, Hocine, Park, Enoch Y., El Enshasy, Hesham A.
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/103989/1/HeshamAliMetwally2022_StreptomycesspADR1StrainProducing%C3%9FandyRubromycin.pdf; http://eprints.utm.my/103989/; http://dx.doi.org/10.3390/fermentation8100473

A Gram-positive strain, ADR1, was isolated from soil collected from the Algerian Sahara Desert. The ethyl acetate extract of the fermentation broth showed cytotoxic activity against the PANC-1 cell line (37.1 ± 1.3% viability when applied at a concentration of 100 µg/mL). Fractionation and NMR analy...