Chemosensing properties of coumarin derivatives: promising agents with diverse pharmacological properties, docking and DFT investigation

• Main Authors: Al-Hazmy, Sadeq M., Zouaghi, Mohamed Oussama, Al-Johani, Jamal N., Arfaoui, Youssef, Hussien Ahmed Al-Ashwal, Rania, Hammami, Bechir, Alhagri, Ibrahim A., Alhemiary, Nabil A., Hamdi, Naceur
• 格式: Article
• 語言: English
• 出版: MDPI 2022
• 主題: Q Science (General)
• 在線閱讀: http://eprints.utm.my/103337/1/RaniaHussienAhmed2022_ChemosensingPropertiesofCoumarinDerivatives.pdf; http://eprints.utm.my/103337/; http://dx.doi.org/10.3390/molecules27185921

In this work, a three-component reaction of 3-acetyl-4-hydroxycoumarine, malononitrile, or cyanoacetate in the presence of ammonium acetate was used to form coumarin derivatives. The chemical structures of new compounds were identified by 1H, 13C NMR and an elemental analysis. These compounds were e...