Chiral separation of ketoconazole and itraconazole anti-fungal drugs using experimental and computational approaches
Drugs with multiple chiral centers were observed as very effective for treating various diseases. However, the enantiomeric resolution of multiple chiral center racemates is not much developed compared to racemates having a single asymmetric center. This work aimed to develop a chiral separation met...
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Format: | Thesis |
Language: | English |
Published: |
2019
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Online Access: | http://eprints.utm.my/id/eprint/101945/1/SitiRosilahPhDFS2019.pdf http://eprints.utm.my/id/eprint/101945/ http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:145993 |
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