Preliminary study of structural changes of Glucose-6-phosphate dehydrogenase deficiency variants

• Main Authors: Louis, Naveen E., Hamza, Muaawia A., Engku Baharuddin, Puteri N. S. D., Chandran, Shamini, A. Latif, Nurriza, Alonazi, Mona A., Halim, Khairul B. A., Warsy, Arjumand, Amran, Syazwani I.
• Format: Article
• Language: English
• Published: China Medical University 2022
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/id/eprint/101238/1/NurrizaAbLatif2022_PreliminaryStudyofStructuralChangesofGlucose6Phosphate.pdf; http://eprints.utm.my/id/eprint/101238/; http://dx.doi.org/10.37796/2211-8039.1355

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency disorder affecting over 400 million individuals worldwide. G6PD protects red blood cells (RBC) from the harmful effects of oxidative substances. There are more than 400 G6PD mutations, of which 186 variants have...