Utilizing shared interacting domain patterns and gene ontology information to improve protein–protein interaction prediction

• Main Authors: Roslan, Rosfuzah, M. Othman, Razib, A.Shah, Zuraini, Kasim, Shahreen, Asmuni, Hishammuddin, Taliba, Jumail, Hassan, Rohayanti, Zakaria, Zalmiyah
• Format: Article
• Published: Elsevier 2010
• Subjects: QA75 Electronic computers. Computer science
• Online Access: http://eprints.utm.my/id/eprint/10027/; http://dx.doi.org/10.1016/j.compbiomed.2010.03.009

Protein–protein interactions (PPIs) play a significant role in many crucial cellular operations such as metabolism, signaling and regulations. The computational methods for predicting PPIs have shown tremendous growth in recent years, but problem such as huge false positive rates has contributed to...